ISABELLE KONE-PAUT

Head of Pediatric Rheumatology Dept, Kremlin Bicêtre Hospital, FRANCE

Professor Isabelle Koné-Paut is the head of a world-renowned pediatric rheumatology department at the Kremlin Bicêtre hospital, university of Paris Sud-Saclay. Her department has been awarded EULAR Center of Excellence 2015/2020 with the Adult Rheumatology Department (Pr Xavier Mariette). 

 

 

Prof Koné-Paut coordinates the national reference center for rare autoinflammatory diseases and inflammatory amyloidosis (CEREMAI then CEREMAIA (http://www.ceremaia.fr) since 2007 which has 5 constitutive sites: Versailles: Dr. Hentgen, Tenon: Prof. Grateau, La Pity: Pr Saadoun, Montpellier: Pr Touitou). CEREMAIA is a member of the rare autoimmune and autoinflammatory systemic diseases French network: FAI2R. The Pediatric rheumatology team is a member of the European rare diseases network: RITA. The pediatric rheumatology department and CEREMAIA support children and adolescents with inflammatory rheumatisms (juvenile arthritis, spondyloarthritis), connective tissue diseases (lupus, scleroderma, inflammatory myopathies) and systemic vasculitis.  More than 300 patients with autoinflammatory disease are seen every year. Particularly invested in clinical research, Professor Koné-Paut collaborates in a number of European and international initiatives: EUROFEVER, JIR cohort, PEDBD, IMMUNAID, and she has developed with her team the first score to measure the activity of autoinflammatory diseases: AIDAI at the service of patients and research. The creation of evaluation tools in the field of AIDs remains a priority in the clinical research of the department. Basic / translational research is developing in the area of AIDs and vasculitis with the CRB and the INSERM immunology unit of the southern GHU. The service has initiated and / or participated in more than 30 clinical trials and therapeutic trials since 2006. Professor Koné-Paut is the author of numerous international publications, the most significant of which concern Behçet's disease, familial Mediterranean fever, CAPS syndromes and Kawasaki disease. She has held various positions in academic societies: President of SOFREMIP (French society of pediatric rheumatology), board member of the French Society of Pediatrics, PRES, ISSAID, the International Society of Behçet (ISBD). She created with Pr Touitou an inter universities diploma of autoinflammatory diseases in 2016. Finally, Professor Koné-Paut created the first pediatric inflammatory rheumatism care network (RESRIP: http://www.resrip.fr) in the area of Paris ile de France in 2012.

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